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2-hydroxy Flutamide

CAS No. 52806-53-8

2-hydroxy Flutamide( —— )

Catalog No. M20966 CAS No. 52806-53-8

2-hydroxy Flutamide is competitive inhibition of androgen receptor (AR)?for the treatment of prostate cancer.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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10MG 72 Get Quote
25MG 140 Get Quote
50MG 215 Get Quote
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Biological Information

  • Product Name
    2-hydroxy Flutamide
  • Note
    Research use only, not for human use.
  • Brief Description
    2-hydroxy Flutamide is competitive inhibition of androgen receptor (AR)?for the treatment of prostate cancer.
  • Description
    2-hydroxy Flutamide is competitive inhibition of androgen receptor (AR)?for the treatment of prostate cancer.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Endocrinology/Hormones
  • Target
    Androgen Receptor (AR)
  • Recptor
    Androgen Receptor
  • Research Area
    Cancer
  • Indication
    Prostate Cancer

Chemical Information

  • CAS Number
    52806-53-8
  • Formula Weight
    292.21
  • Molecular Formula
    C11H11F3N2O4
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:25mg/ml(85.5 mM)
  • SMILES
    CC(C)(O)C(=O)Nc1ccc([N+](=O)[O-])c(C(F)(F)F)c1
  • Chemical Name
    2-hydroxy-2-methyl-N-(4-nitro-3-(trifluoromethyl)phenyl)propanamide

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Blobaum A L Byers F W Bridges T M et al. A Screen of Approved Drugs Identifies the Androgen Receptor Antagonist Flutamide and Its Pharmacologically Active Metabolite 2-Hydroxy-Flutamide as Heterotropic Activators of Cytochrome P450 3A In Vitro and In Vivo.[J]. Drug Metabolism & Disposition the Biological Fate of Chemicals 2015 43(11):1718.
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